Bioengineering Labs + Facilities
Bioengineering Primary Faculty Labs:
Dani S. Bassett – The Complex Systems Lab studies biological, physical, and social systems by using and developing tools from network science and complex systems theory.
Joel D. Boerckel – The Developmental Mechanobiology and Regeneration Lab seeks to understand how mechanical cues influence embryonic development to enable tissue engineering strategies that recapitulate these processes for regeneration.
Greg Bowman – The Bowman Lab devises new ways to develop therapeutics and interpret genetic variation by understanding/exploiting protein dynamics using a combination of biophysical experiments, machine learning, physics-based simulations, and the world’s largest distributed computer.
Lukasz Bugaj – The Bugaj Lab studies the mechanisms that govern essential cell decisions like growth, differentiation, and death, specializing in using light-activatible tools that can probe living cells in real-time with exquisite precision.
Zhiliang Cheng – The Cheng Lab develops new nanotechnology for better understanding of biology, early diagnosis of disease, monitoring therapy response, and for guiding drug discovery/development.
Jennifer Cremins – The Cremins Lab aims to understand how chromatin works through long-range physical folding mechanisms to encode neuronal specification and long-term synaptic plasticity in healthy and diseased neural circuits.
Daniel Hammer – The Hammer Lab develops quantitative tools to analyze or mimic biology with particular interest in the role of cell adhesion and motility in the immune response.
Alex Hughes – The Hughes Lab in developmental engineering works to bring developmental processes that operate in vertebrate embryos and regenerating organs under an engineering control framework, so that we can build better tissues.
Dan Huh – The BIOLines Laboratory focuses on developing innovative bioengineering technologies based on biologically inspired design principles and engineering strategies to improve human health and promote environmental sustainability.
David Issadore – The Issadore Lab combines microelectronics, microfluidics, nanomaterials, and machine learning to solve big problems in healthcare.
Jenny Jiang – The Jiang Lab in systems immunology and immune engineering uses high-throughput sequencing and single-cell analysis in combination with quantitative analysis to answer key questions about the immune system.
Jina Ko – The Ko Lab develops novel technologies using bioengineering, molecular biology, and chemistry tools to address currently intractable diagnostic challenges for precision medicine.
Konrad Kording – The Kording Lab in data science studies deep learning and its applications, neural data analysis, and causality and its links with machine learning.
Brian Litt – The Litt Lab in translational neuroengineering translates neuroengineering research directly into patient care, collaborating broadly across disciplines to invent, develop and test new technologies and apply them to basic and clinical research.
Claudia Loebel – The Loebel Lab develops biomaterials and engineering technologies to improve our understanding of how cells interact with their extracellular microenvironment. By applying in vitro and in vivo models our goal is to probe tissue regeneration and repair in diseases such as fibrotic, congenital and inflammatory disorders, and with a particular focus on the pulmonary system
David Meaney – The Molecular Neuroengineering Lab for Traumatic Brain Injury studies concussion with a variety of methods and tools that include in vivo, in vitro, and in silico models of injury.
Michael Mitchell – The Mitchell Lab lies at the interface of biomaterials science, drug delivery, and cellular and molecular bioengineering to fundamentally understand and therapeutically target biological barriers.
Noor Momin – The Momin Lab seeks to understand and develop treatment and diagnostics for cardiovascular diseases by leveraging our expertise in cardiovascular immunology, protein engineering, and pharmacokinetic modeling.
Alison Pouch – The Pouch Lab in the Penn Image Computing and Science Laboratory (PICSL) develops computational 3D/4D medical image analysis algorithms with an emphasis on applications to surgical planning for the treatment of heart valve disease.
Ravi Radhakrishnan – The Radhakrishnan Lab provides molecular level characterization of complex biomolecular systems and formulates quantitatively accurate microscopic models for predicting the interactions of various therapeutic agents with innate biochemical signaling mechanisms.
Arjun Raj – The Raj Lab for Systems Biology is interested in building a quantitative understanding of cellular function, developing new tools for quantifying biological processes based on imaging and sequencing, and using those techniques to answer questions in molecular and cellular biology.
Sydney Shaffer – The Shaffer Lab is focused on understanding how differences between single-cells generate phenotypes such as drug resistance, oncogenesis, differentiation, and invasion. They are an interdisciplinary team of engineers, physicists, biologists, and clinicians.
Yihui Shen – The Shen Lab takes an interdisciplinary approach from optical microscopy to multi-omics to measure metabolism
and understand metabolic regulation.
Aaron Timperman – The Timperman Lab develops novel microfluidic and nanofluidic systems for applied and fundamental studies that integrate engineering, chemistry, biology, and physics to improve human and environmental health.
Andrew Tsourkas – The Tsourkas Lab in Targeted Imaging Therapeutics and Nanomedicine (TITAN) is interested in creating novel targeted imaging and therapeutic agents for the detection and/or treatment of diverse diseases.
Flavia Vitale – The Vitale Lab creates novel technologies to study, monitor and treat neurological and neuromuscular disorders such as epilepsy, Parkinson’s, nerve injury, and chronic pain.
Beth Winkelstein – The Spine Pain Research Lab (SPRL) focuses on defining and understanding specific mechanisms of chronic neck pain and linking injury mechanics to the cellular and molecular substrates of persistent pain.
Shared Bioengineering Research Resources:
Visit the Shared Research Equipment page on the BE Research website for a list of equipment and technologies available for use in the Department of Bioengineering. Use of the shared resources is restricted to laboratory groups associated with Bioengineering faculty and their collaborators.