Bioengineering Research Areas

Research within the Department of Bioengineering transcends many disciplines and includes faculty and resources that span the entire University including the medical and veterinary schools, the School of Arts and Sciences, and colleagues in the School of Engineering and Applied Science.  Projects involve observing and manipulating living systems over many length scales, from the small (molecular) to the large (physiome), and are aimed at creating new knowledge and technology to better understand fundamental biological processes and improve clinical practice and patient care.  Much of the research capitalizes on our unique ties with clinicians, enabling the translation from bench to bedside.  Bioengineering research at Penn falls broadly into 16 main categories.  The Bioengineering Graduate Group faculty members involved in each research area are listed with each description below.

Molecular Engineering

Molecular engineering involves manipulating genes, RNA, proteins, enzymes and small molecules to better understand their structure-function relationship, introduce new functionality, improve function and/or impair function. Applications include designing better therapies; manipulating the operation of molecular networks and consequently cellular behavior, generating molecular devices for use in synthetic biology, and developing new molecular imaging agents that can be used to report cell processes.

Affiliated Graduate Group Faculty:

Irfan A. Asangani, Ph.D.

Juan Alvarez, Ph.D.

Gerd Blobel, MD, PhD

Roberto Bonasio, M.D., Ph.D.

Greg Bowman, Ph.D.

Jake Brenner, M.D., Ph.D.
Lukasz Bugaj, PhD

Alice Chen-Plotkin, M.D.
David M. Chenoweth, PhD
Lewis Chodosh, MD, PhD
John Crocker, PhD

Beverly L. Davidson, Ph.D.

Yanxiang Deng, Ph.D.
Joshua Dunaief, MD, PhD
R. Babak Faryabi, PhD
Jay Gottfried, MD, PhD
Riccardo Gottardi, Ph.D.
Daniel A. Hammer, PhD
Meenhard Herlyn, DVM, DSc
David Issadore, PhD
Junhyong Kim, PhD
Jina Ko, PhD

Rahul M. Kohli,M.D., Ph.D.
Michel Koo, DDS, PhD
Daqing Li, MD

Qi Long, Ph.D.
Wenquin Luo, MD, PhD

Leyuan Ma, Ph.D.
Mustafa Mir, Ph.D
Michael J. Mitchell, PhD

Noor Momin, PhD
John Isaac Murray, PhD

Kiran Musunuru, M.D., Ph.D.

Liming Pei, Ph.D.
Jennifer E. Phillips-Cremins, PhD
Avery D. Posey, Ph.D 
Daniel Rader, MD
Ravi Radhakrishnan, PhD
Arjun Raj, PhD

Bushra Raj, Ph.D.
Harvey Rubin, MD, PhD
Marco Ruella, MD
Mark A. Sellmyer, MD, PhD

Nik Sgourakis, Ph.D.
Sydney Shaffer, MD, PhD
Li Shen, Ph.D.
H. Lee Sweeney, PhD
Kai Tan, Ph.D.

Cory Tschabrunn, Ph.D.
Andrew Tsourkas, PhD

Golnaz Vahedi,Ph.D.
Sergei Vinogradov, PhD
Kai Wang, PhD
Ping Wang, DABCC, FAACC, PhD
John Weisel, PhD

David Weiner,Ph.D.
Yi Xing, Ph.D.

Ken Zaret, Ph.D.

Zhaolan (Joe) Zhou, Ph.D.

Cellular Engineering

Cellular engineering involves applying the principles and methods of the physical and biological sciences to study and manipulate cellular systems. Research directions within cellular engineering include cell mechanics, mechanotransduction, cell-cell interactions, cell-matrix interactions, and cell differentiation.  Faculty are also working to engineer cells with enhanced metabolic function (e.g., liver), using cells as a vehicle for cell-based gene delivery, stimulating and/or differentiating cells to better recognize and fight disease, and many additional applications where cells are being harnessed to treat disease.

Affiliated Graduate Group Faculty:

Juan Alvarez, Ph.D.

Zoltan Arany, MD, PhD

Irfan A. Asangani, Ph.D.

Joseph Baur, Ph.D.

Roberto Bonasio, M.D., Ph.D.
Lukasz Bugaj, PhD

Alice Chen-Plotkin, M.D.
Lewis Chodosh, MD, PhD
John Crocker, PhD

Yanxiang Deng, Ph.D.
Dennis E. Discher, PhD

R. Babak Faryabi, PhD
Saar Gill, MD, PhD
Yale E. Goldman, MD, PhD

Roger Greenberg, M.D.
Mark Goulian, PhD

Marie Guerraty, M.D., Ph.D.
Daniel A. Hammer, PhD
Su Chin Heo,Ph.D.
Meenhard Herlyn, DVM, DSc
Alex J. Hughes, PhD
Dongeun (Dan) Huh, PhD
David Issadore, PhD
Paul A. Janmey, PhD

Carl June, Ph.D. 
Jina Ko, PhD
Daqing Li, MD

Fanxin Long, Ph.D.
Wenquin Luo, MD, PhD

Leyuan Ma, Ph.D.
Kenneth B. Margulies, MD
David F. Meaney, PhD
Michael J. Mitchell, PhD

Noor Momin, PhD
John Isaac Murray, PhD

Kiran Musunuru, M.D., Ph.D.

Guilherme Nader, Ph.D.

Liming Pei, Ph.D.
Jennifer E. Phillips-Cremins, PhD
Avery D. Posey, Ph.D 
Ling Qin, Ph.D.
Daniel Rader, MD
Ravi Radhakrishnan, PhD
Marco Ruella, MD
Mark A. Sellmyer, MD, PhD
Sydney Shaffer, MD, PhD

Nik Sgourakis, Ph.D.
Junwei Shi, Ph.D.
Kai Tan, Ph.D.
Phong Tran, Ph.D.
Cory Tschabrunn, Ph.D.

Rebecca Wells, MD
Yi Xing, Ph.D.

Ken Zaret, Ph.D.
Zhaolan (Joe) Zhou, Ph.D.

Rong Zhou, PhD

Tissue Engineering

Tissue engineering refers to the engineering of synthetic and/or biological samples for use as tissue implants, to support tissue growth, or as platforms for therapeutic applications. Tissue engineering has resulted in both clinically used and experimental therapies for structural tissue repair (e.g., skin, bone, cartilage, tendon, muscle, and blood vessel) and replacement. Tissue engineering constructs have also been used to deliver drugs and/or provide a platform for cell-based therapies.

Affiliated Graduate Group Faculty:

Juan Alvarez, Ph.D.

Zoltan Arany, MD, PhD

Joseph Baur, Ph.D.

Joel Boerckel, Ph.D.
Lukasz Bugaj, PhD
Jason Burdick, PhD

Yanxiang Deng, Ph.D.

Yi Fan, Ph.D. 
Robert C. Gorman, MD
Riccardo Gottardi, PhD

Sarah Gullbrand, Ph.D.
Su Chin Heo,Ph.D.
Meenhard Herlyn, DVM, DSc
Alex J. Hughes, PhD
Dongeun (Dan) Huh, PhD

Kyu Sang Joeng, Ph.D.

Fanxin Long, Ph.D.

Christopher Madl, Ph.D.
Kenneth B. Margulies, MD
Robert Mauck, PhD
Michael J. Mitchell, PhD

Noor Momin, PhD
Ling Qin, PhD
Lachlan J. Smith, PhD
Louis J. Soslowsky, PhD
Christoph Thaiss, PhD

Cory Tschabrunn, Ph.D.

Kyle Vining, Ph.D.
Susan W. Volk, VMD, PhD
Rebecca Wells, MD

Ken Zaret, Ph.D.

Bioengineered Therapeutics, Devices and Drug Delivery

The development of drug and gene delivery systems involves the synthesis of novel materials, the preparation of micro- and nanoplatforms, innovations in targeting, controllable drug release, and biodegradation and the mathematical modeling of these systems.  Applications associated with drug and gene delivery systems include controlling stem-cell differentiation, treating disease, modulating organ function, and/or controlling the immune system.  Optimization of drug delivery systems can involve mathematical modeling of nanoparticle targeting, modeling normal and diseased human tissue microenvironment, and studying drug uptake and processing.

Affiliated Graduate Group Faculty:

Juan Alvarez, Ph.D.

Wesley Baker, Ph.D.

Jake Brenner, MD, PhD
Jason Burdick, PhD
David M. Chenoweth, PhD

Zhiliang Cheng, Ph.D.
Lewis Chodosh, MD, PhD
Michael Chorny, PhD
Artur Cideciyan, PhD
David P. Cormode, PhD

Beverly L. Davidson, Ph.D.
Yanxiang Deng, Ph.D.

Scott Diamond, PhD
Eric S. Diffenderfer, PhD
Dennis E. Discher, PhD
Joshua Dunaief, MD, PhD
Marni Falk, PhD

Yi Fan, Ph.D. 
Victor Ferrari, MD
Mark A. Fogel, MD
Saar Gill, MD, PhD
Daniel A. Hammer, PhD
Meenhard Herlyn, DVM, DSc
Dongeun (Dan) Huh, PhD

Geelsu Hwang, Ph.D.
Paul A. Janmey, PhD
Yuanwen Jiang, Ph.D.

Jina Ko, PhD
Daeyeon Lee, PhD
Robert J. Levy, MD
Daqing Li, MD

Fanxin Long, Ph.D.

Leyuan Ma, Ph.D.
Michael J. Mitchell, PhD

Noor Momin, PhD
Vladimir Muzykantov, MD, PhD
Warren Pear, MD, PhD

Liming Pei, Ph.D.
Daniel Rader, MD
Arjun Raj, PhD
Harvey Rubin, MD, PhD
Marco Ruella, MD

Carla R. Scanzello, M.D., Ph.D.
Mark A. Sellmyer, MD, PhD

Nik Sgourakis, Ph.D.
Lachlan J. Smith, PhD
Stanley Stachelek, PhD
H. Lee Sweeney, PhD
Cory Tschabrunn, Ph.D.

Andrew Tsourkas, PhD
Susan W. Volk, VMD, PhD
Kai Wang, PhD
Ping Wang, DABCC, FAACC, PhD
William C. Welch, MD, FAANS, FACS, FICC
Walter RT Witschey, PhD

Ying Xiao, Ph.D.
Rong Zhou, PhD

Cardiovascular and Pulmonary Cell and Tissue Mechanics

Cardiovascular and pulmonary cell and tissue mechanics include how endothelial, epithelial, and myocardial cells interact with their environment, and use this knowledge to control cell function and understand disease.  Specific areas of interest include understanding the relationship between mechanical forces and biochemical signaling and the role of gene transcription factors in lung and heart development and disease, myocardial remodeling, utilizing cardiopulmonary bypass to optimize gene delivery, and designing microfluidic devices to study the flux of pro-coagulant molecules to investigate the stability of thrombi.

Affiliated Graduate Group Faculty:

Zoltan Arany, MD, PhD
Peter F. Davies, PhD
Scott Diamond, PhD
Dennis E. Discher, PhD
Victor Ferrari, MD
Mark A. Fogel, MD
James C. Gee, PhD
Robert C. Gorman, MD
Riccardo Gottardi, PhD

Marie Guerraty, M.D., Ph.D.
Daniel A. Hammer, PhD
Paul A. Janmey, PhD
Robert J. Levy, MD
Kenneth B. Margulies, MD
Michael J. Mitchell, PhD

Noor Momin, PhD

Liming Pei, Ph.D.
Daniel Rader, MD
Chandra Sehgal, PhD

Arndt F. Siekmann, PhD
H. Lee Sweeney, PhD

Cory Tschabrunn, Ph.D.

David Weiner,Ph.D.

Walter RT Witschey, PhD

Orthopaedic Bioengineering

Orthopaedic Bioengineering employs biomechanics, biomaterials, and cell and tissue engineering to the study of injury, degeneration, repair, and regeneration of orthopaedic tissues such as bone, cartilage, tendons, ligaments, and intervertebral discs. At the University of Pennsylvania, our program encompasses all levels of orthopaedic research from joints, to tissues, to cells and molecules.

Affiliated Graduate Group Faculty:

Kristy Arbogast, PhD
Josh R. Baxter, Ph.D
Zhiliang Cheng, Ph.D.
James C. Gee, PhD
Riccardo Gottardi, Ph.D.
Eric J. Granquist, DMD, MD

Sarah Gullbrand, Ph.D.
Su Chin Heo,Ph.D.
Kyu Sang Joeng, Ph.D.

Tejvir S. Khurana, MD, PhD
Xiaowei Sherry Liu, PhD

Fanxin Long, Ph.D.
Robert Mauck, PhD
Michael J. Mitchell, PhD
Foteini Mourkioti, Ph.D.
Ling Qin, Ph.D.

Chamith Rajapakse, Ph.D.
Ravinder Reddy, PhD

Carla R. Scanzello, M.D., Ph.D.

Eileen M. Shore, PhD
Lachlan J. Smith, PhD
Hee Kwon Song, PhD
Louis J. Soslowsky, PhD

Ottman Tertuliano, Ph.D.
Susan W. Volk, VMD, PhD
Felix W. Wehrli, PhD
Beth A. Winkelstein, PhD
Walter RT Witschey, PhD

Injury Biomechanics

Injury Biomechanics is the study of how cells and tissues respond when exposed to mechanical forces, with a focus on the complex relationships between early and long-term changes in structure and function. With this knowledge, new intervention strategies are being developed to improve cell and tissue recovery from injury. In addition, the investigators measure tissue mechanical properties and injury thresholds, and develop computational models to generalize the cell and tissue results to a macroscopic level and determine injury mechanisms.  These studies parallel clinical investigations regarding the treatment and detection of traumatic injury. Applications of current work are in the areas of traumatic brain and spine injury in adults and children, and ventilator-induced lung injury.

Affiliated Graduate Group Faculty:

Kristy Arbogast, PhD
Akiva Cohen, PhD
D. Kacy Cullen, PhD
M. Sean Grady, MD
Eric J. Granquist, DMD, MD
Su Chin Heo,Ph.D.

Michelle Johnson, Ph.D.
Kelly Jordan-Sciutto, PhD

Matthew R. Maltese, Ph.D.
David F. Meaney, PhD
Foteini Mourkioti, PhD

Eileen M. Shore, PhD
Douglas H. Smith, MD

Susan W. Volk, VMD, PhD
Beth A. Winkelstein, PhD

Cell Mechanics

The field of cell mechanics, a subset of cellular engineering, seeks to understand how cells interact mechanically with their environment and to use this knowledge to control cell function and understand disease and repair processes. Faculty research spans molecular and cell biophysics and polymer engineering, the regulation of angiogenesis and stem cell biology, the stress response in medical and psychiatric disorders, the cellular and molecular mechanisms of traumatic brain injury, and the mechanical factors in liver fibrosis.

Affiliated Graduate Group Faculty:

Akiva Cohen, PhD
John Crocker, PhD
Yanxiang Deng, Ph.D.

Dennis E. Discher, PhD

Yi Fan, Ph.D. 
Yale E. Goldman, MD, PhD
Riccardo Gottardi, PhD
Daniel A. Hammer, PhD
Su Chin Heo,Ph.D.
Alex J. Hughes, PhD
Paul A. Janmey, PhD
Junhyong Kim, PhD

Christopher Madl, Ph.D.
Kenneth B. Margulies, MD
David F. Meaney, PhD
Mustafa Mir, PhD
Michael J. Mitchell, PhD
Foteini Mourkioti, PhD

Guilherme Nader, Ph.D.

Eileen M. Shore, PhD
Arndt F. Siekmann, PhD

Ottman Tertuliano, Ph.D.
Phong Tran, Ph.D.

Kyle Vining, Ph.D.
Rebecca Wells, MD

Biomaterials

Biomaterials are being developed that are biocompatible, degradable, support tissue formation, encourage/discourage cell attachment, growth, and differentiation, provide platforms for the controlled release of growth factors, cytokines, drugs or antibiotics, and promote the formation of extracellular matrix.  Further, a wide range of processing techniques are used and/or developed to fabricate scaffolds and particles with the desired nano-,  micro-, and macroscopic structures.

Affiliated Graduate Group Faculty:

Danielle Bassett, PhD
Dawn Bonnell, PhD
Zhiliang Cheng, Ph.D.
David M. Chenoweth, PhD
Michael Chorny, PhD
Russell J. Composto, PhD
David P. Cormode, PhD

Yanxiang Deng, Ph.D.

Dennis E. Discher, PhD
Riccardo Gottardi, PhD
Daniel A. Hammer, PhD
Su Chin Heo, PhD
Alex J. Hughes, PhD

Geelsu Hwang, Ph.D.
Daeyeon Lee, PhD
Robert J. Levy, MD
Daqing Li, MD

Christopher Madl, Ph.D.
Robert Mauck, PhD
Michael J. Mitchell, PhD
Vladimir Muzykantov, MD, PhD

Nik Sgourakis, Ph.D.
Cory Tschabrunn, Ph.D.

Andrew Tsourkas, PhD

Kyle Vining, Ph.D.
Susan W. Volk, VMD, PhD
John Weisel, PhD

Systems and Synthetic Bioengineering

The new field of systems and synthetic bioengineering focuses on understanding how molecular and cellular processes interact to produce function at the cellular and organism level.  This understanding is used to engineer cells to perform specific functions and to develop new synthetic diagnostic methods and therapeutics to treat diseases from cancer to diabetes.  Using both experimental and computational methods, applications include neuroscience, cell signaling, protein engineering, and developmental biology.

Affiliated Graduate Group Faculty:

Dani Bassett, PhD
Lukasz Bugaj, PhD
Lewis Chodosh, MD, PhD

Cesar de la Fuente, Ph.D.
R. Babak Faryabi, PhD

Alex J. Hughes, PhD
Junhyong Kim, PhD
Michael J. Mitchell, PhD
John Isaac Murray, PhD

Bijan Pesaran, Ph.D.
Jennifer E. Phillips-Cremins, PhD
Arjun Raj, PhD

Yihui Shen, Ph.D.
Mark A. Sellmyer, MD, PhD

Nik Sgourakis, Ph.D.

Sydney Shaffer, MD, PhD
Kai Tan, Ph.D.

Computational Neuroengineering

Computational Neuroengineering is the study of neural function through the use of computer simulation, hardware-based modeling, and mathematical analysis, in concert with physiological and psychophysical experiments. The goal is to use engineering analysis to uncover the principles of neural function in health, disease, and degeneration.

Affiliated Graduate Group Faculty:

Danielle Bassett, PhD

Michael Beauchamp, Ph.D.
David Brainard, PhD
Iahn Cajigas, M.D. Ph.D.

Yale Cohen, PhD
Douglas Coulter, PhD
John Detre, MD

Yong Fan, Ph.D.
Christopher Fang-Yen, PhD
James C. Gee, PhD
Maria Geffen, PhD
Michael Kahana, PhD
Brian Litt, MD
Javier Medina, PhD

Bijan Pesaran, Ph.D.

Andrew G. Richardson, Ph.D.
Timothy Roberts, PhD
Li Shen, Ph.D.
Alan A. Stocker, PhD

Flavia Vitale, Ph.D.
Joost Wagenaar, Ph.D.

Kai Wang, PhD

Wanding Zhou, M.D., Ph.D.

Experimental Neuroengineering

Experimental neuroscience investigates fundamental cellular and molecular mechanisms that underlie traumatic brain and neck injuries, epilepsy, neurodegeneration, and stroke; and the role of injury mechanics in the physiology of pain.  Bioengineering applications include designing neuronal networks encoding of peripheral sensor input, implantable neurodevices, optical imaging of blood flow and oxygen, and computational tools to track and modulate brain function.

Affiliated Graduate Group Faculty:

Kristy Arbogast, PhD

Wesley Baker, Ph.D.

Danielle Bassett, PhD

Michael Beauchamp, Ph.D.
Iahn Cajigas, M.D. Ph.D.

Akiva Cohen, PhD
Yale Cohen, PhD
Diego Contreras, MD, PhD
Douglas Coulter, PhD
D. Kacy Cullen, PhD

Beverly L. Davidson, Ph.D.
John Detre, MD
Joshua Dunaief, MD, PhD
James Eberwine, PhD
Nader Engheta, PhD
Christopher Fang-Yen, PhD
Maria Geffen, PhD
Yale E. Goldman, MD, PhD
Jay Gottfried, MD, PhD
M. Sean Grady, MD
Joel H. Greenberg, PhD
Paul A. Janmey, PhD

Yuanwen Jiang, Ph.D.

Michelle Johnson, Ph.D.
Kelly Jordan-Sciutto, PhD
Brian Litt, MD
David F. Meaney, PhD
Javier Medina, PhD

Bijan Pesaran, Ph.D.

Bushra Raj, Ph.D.

Andrew G. Richardson, Ph.D.
Douglas H. Smith, MD
Alan A. Stocker, PhD

Flavia Vitale, Ph.D.
Beth A. Winkelstein, PhD

Zhaolan (Joe) Zhou, Ph.D.

Medical Imaging and Imaging Instrumentation

Research in Biomedical Imaging focuses on the development of new methodology for image acquisition and processing, with the goal of establishing new procedures for clinical diagnosis and therapy response monitoring. The core technologies comprise magnetic resonance (MR), computed tomography (CT), X-ray imaging, nuclear medicine imaging, single photon emission computed tomography (SPECT), positron emission tomography (PET), optical imaging, and ultrasound.

Affiliated Graduate Group Faculty:

Spyridon Bakas, Ph.D.

Wesley Baker, Ph.D.

Dani Bassett, PhD

Michael Beauchamp, Ph.D.

Ari Borthakur, PhD, MBA

Yi-Wei Chang, Ph.D.
Artur Cideciyan, PhD
David P. Cormode, PhD

Sandhitsu (Sandy) Das, Ph.D.
Christos Davatzikos, PhD
E. Jim Delikatny, PhD
John Detre, MD
Eric S. Diffenderfer, PhD
Joshua Dunaief, MD, PhD
Marni Falk, PhD
Christopher Fang-Yen, PhD
Victor Ferrari, MD
Mark A. Fogel, MD

Grace Jianan Gang, Ph.D.
James C. Gee, PhD
Jerry Glickson, PhD
Jay Gottfried, MD, PhD
Eric J. Granquist, DMD, MD

Murray Grossman, M.D., Ed.D.

Marie Guerraty, M.D., Ph.D.

James Gugger, MD, PharmD

Sarah Gullbrand, Ph.D.
Hao Huang, PhD
Joel Karp, PhD

Despina Kontos, PhD
Michel Koo, DDS, PhD
Xiaowei Sherry Liu, PhD
Jennifer M. Lynch, MD, PhD.

Andrew Maidment, PhD

Corey McMillan, Ph.D.

Scott Metzler, Ph.D.
Mustafa Mir, PhD
Jessica I. W. Morgan, PhD

Peter Noel, Ph.D.

Bijan Pesaran, Ph.D.
Alison Pouch, PhD
Ravinder Reddy, PhD
Rahim Rizi, PhD
Timothy Roberts, PhD
Mitchell Schnall, MD, PhD
Chandra Sehgal, PhD
Mark A. Sellmyer, MD, PhD
Li Shen, Ph.D.

Yihui Shen, Ph.D.

Hee Kwon Song, PhD

Joel M. Stein, M.D., Ph.D.

Suleman Surti, PhD
Cory Tschabrunn, Ph.D.

Jayaram K. Udupa, PhD
Sergei Vinogradov, PhD
Felix W. Wehrli, PhD

Brian R. White, MD, PhD
Rodney Wiersma, PhD
Walter RT Witschey, PhD

Ying Xiao, Ph.D.
Arjun Yodh, PhD

Imaging Theory and Analysis

The development of computer-based imaging theory and analysis methods has given rise to applications in a wide variety of clinical research studies, including Alzheimer’s disease, schizophrenia, cardiac diseases, brain cancer, and bone diseases.  Methodologies that are being developed include image registration, segmentation, population-based statistical analysis, biophysical modeling of anatomical deformation, nano- and micro-structural tissue organization, high-dimensional pattern classification, mophometry, and diffusion tensor image processing.  Other novel approaches include pulse sequence development to exploit quadrupolar spin-dynamics, polarization transfer, multiple quantum coherences, and indirect detection and spin locking for studying molecular dynamics in biological tissues in vivo to impart novel contrast in various tissue types.

Affiliated Graduate Group Faculty:

Spyridon Bakas, Ph.D.

Vijay Balasubramanian, PhD
Danielle Bassett, PhD
Ari Borthakur, PhD

Yi-Wei Chang, Ph.D.
Artur Cideciyan, PhD
Christos Davatzikos, PhD
E. Jim Delikatny, PhD
Nader Engheta, PhD
Charles Epstein, PhD

Yong Fan, Ph.D.

R. Babak Faryabi, PhD
Victor Ferrari, MD

Grace Jianan Gang, Ph.D.
James C. Gee, PhD
Hao Huang, PhD

Dokyoon Kim, Ph.D.
Despina Kontos, PhD
Michel Koo, DDS, PhD
Xiaowei Sherry Liu, PhD

Jennifer Lynch, Ph.D.
Andrew Maidment, PhD
Vadim Markel, PhD

Corey McMillan, Ph.D.

Mustafa Mir, Ph.D
Jessica I. W. Morgan, PhD
John Isaac Murray, PhD

Peter Noel, Ph.D.

Alison Pouch, PhD
Ravinder Reddy, PhD
Timothy Roberts, PhD
Mitchell Schnall, MD, PhD
Chandra Sehgal, PhD

Li Shen, Ph.D.
Hee Kwon Song, PhD
Jayaram K. Udupa, PhD
Lyle H. Ungar, PhD
Ragini Verma, PhD
Sergei Vinogradov, PhD

Brian R. White, MD, PhD
Walter RT Witschey, PhD

Ying Xiao, Ph.D.

Arjun Yodh, PhD
Paul Yushkevich, PhD
Timothy Zhu, PhD

Imaging Theory and Analysis

Molecular imaging sets forth to probe the molecular abnormalities of disease rather than image the end effects of these molecular alterations.  Topics of research being pursued include the development of contrast agents, the preparation of biodegradable micro- and nanoplatforms, bioconjugate techniques, and the development of new targeting strategies.  Cellular imaging involves the non-invasive tracking of cells populations in living subjects.  These techniques are being developed and employed to monitor cell-based therapies, to monitor the cellular immune response following mechanical insults, infection, or disease, and to track the efficacy of various therapeutics.

Affiliated Graduate Group Faculty:

Gerd Blobel, MD, PhD
Lukasz Bugaj, PhD

Yi-Wei Chang, Ph.D.
David M. Chenoweth, PhD
Akiva Cohen, PhD
David P. Cormode, PhD
Douglas Coulter, PhD
E. Jim Delikatny, PhD
Joshua Dunaief, MD, PhD
Victor Ferrari, MD

Terence Gade, M.D., Ph.D.
Jerry Glickson, PhD
Jay Gottfried, MD, PhD

Roger Greenberg, M.D.
Mark Goulian, PhD

Marie Guerraty, M.D., Ph.D.
Daniel A. Hammer, PhD
Su Chin Heo, PhD
David Issadore, PhD
Kelly Jordan-Sciutto, PhD
Jina Ko, PhD
Michel Koo, DDS, PhD
Daqing Li, MD

Bomyi Lim, Ph.D.

David Mankoff, Ph.D.
Mustafa Mir, PhD
Jessica I. W. Morgan, PhD
Foteini Mourkioti, PhD
John Isaac Murray, PhD

Guilherme Nader, Ph.D.

Bijan Pesaran, Ph.D.
Ling Qin, Ph.D.
Arjun Raj, PhD

Bushra Raj, Ph.D.
Mark A. Sellmyer, MD, PhD
Sydney Shaffer, MD, PhD
Arndt F. Siekmann, PhD

Joel M. Stein, M.D., Ph.D.
Kai Tan, PhD
Phong Tran, Ph.D.
Andrew Tsourkas, PhD

Golnaz Vahedi,Ph.D.
Sergei Vinogradov, PhD
Susan W. Volk, VMD, PhD
John Weisel, PhD
Rong Zhou, PhD

Theoretical and Computational Bioengineering

Theoretical and Computational Bioengineering aims to employ concepts from applied mathematics, physics, and chemistry, infrastructure from computer science and broad-based principles from engineering to gain insight into complex biological systems.  Projects involve the study of biological systems across the atomic, molecular, cellular, tissue and system scales. Hence the field of theoretical and computational bioengineering is inherently interdisciplinary and very diverse in its scope.

Affiliated Graduate Group Faculty:

Juan Alvarez, Ph.D.

Irfan A. Asangani, Ph.D.

Norman Badler, Ph.D.

Danielle Bassett, PhD

Michael Beauchamp, Ph.D.

Roberto Bonasio, M.D., Ph.D.

Greg Bowman, Ph.D.
David Brainard, PhD
Jake Brenner, MD, PhD
Iahn Cajigas, M.D. Ph.D.

Christos Davatzikos, PhD

Cesar de la Fuente, Ph.D.
Scott Diamond, PhD
Dennis E. Discher, PhD
Nader Engheta, PhD
Charles Epstein, PhD
R. Babak Faryabi, PhD
James C. Gee, PhD
Maria Geffen, PhD

Pablo Gonzalez Camara, Ph.D.
Robert C. Gorman, MD
Mark Goulian, PhD
Daniel A. Hammer, PhD

Ingo Helbig, M.D.
Hao Huang, PhD

Dokyoon Kim, Ph.D.

Junhyong Kim, PhD
Despina Kontos, PhD

Qi Long, Ph.D.
Javier Medina, PhD

Noor Momin, PhD

Bijan Pesaran, Ph.D.
Jennifer E. Phillips-Cremins, PhD
Ravi Radhakrishnan, PhD
Arjun Raj, PhD
Timothy Roberts, PhD
David Roos, PhD

Mitchell Schnall, M.D., Ph.D.

Nik Sgourakis, Ph.D.
Li Shen, PhD
Junwei Shi, PhD
Alan A. Stocker, PhD
Kai Tan, PhD
Jayaram K. Udupa, PhD
Lyle H. Ungar, PhD

Golnaz Vahedi,Ph.D.

Joost Wagenaar, Ph.D.

Kai Wang, PhD
John Weisel, PhD
Rodney Wiersma, PhD
Walter RT Witschey, PhD

Ying Xiao, Ph.D.
Yi Xing, PhD
Paul Yushkevich, PhD

Wanding Zhou, M.D., Ph.D.